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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3d594b6598fe001185c97386228411341880d74eaf51a028607170a5d58859' 
  AND token = '6aANAQuLIUd2Wpws25YfROQnw86zpTzHPflsDKlM1mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}