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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53740ba2b80cbffa49f85d147ffc4b69251b2af69d6afcf9f6452cb2ea08c752' 
  AND token = 'XVypiwrA9O27WvowTus67bUtQNjwS/TFIdZvL8qnN/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}