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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5821aa58c5f7c5cad99db36b8a2e46abd3b188b6e184ef622859eb03e0c8006' 
  AND token = 'rq53rusu7PPlkqMAT6qXXVkq2NZISxFowKv1T6FT3Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}