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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54489c3ea175c96dab34746877a22ea6a7aedfbc990d9f0f5d0755433eab76b5' 
  AND token = 'nuZ+5v7eHbBPFfRZCC+gd03ro1+C9wX39EtZNG/8plw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}