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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5da00fd406119259722550971b83fb6d7a7a2b63c5e9e1b17340d8e9e00c74' 
  AND token = 'tDNwMhgVmrEepQr0SdVqGFqvWmqJubDfo6QQro0QyRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}