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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e83889b070fe911ece5733767615914e1009548d65dce3ef906c168d2f6fadf8' 
  AND token = 'ZLRrQL+xYYu38CvwI+pBMPFViPu/el8NC69ikp1acb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}