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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83e9180fdcf50f6b12e392c5ff2439c8e7c1218654a9a2de3877af997ed1dc4b' 
  AND token = 's+Q3w5r+0g2DynnmKMthE95chTlsbmkJJqfE2bOTvNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}