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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5cd8c0ab655330d180454cb1af82bf999b51256f3b37c5546db8bf48e380da' 
  AND token = 'Bo/you7ULF1xS/l4wALaZs9PBtVlMEVBpi2itu49fp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}