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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e222e3153075fbae487b851063ff847338a6834e3873e54b8e856f67113fb51' 
  AND token = 'nOFhxcQl/IOTkL9+Aah2AFr42N4x8REe9cUEOc/jr+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}