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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2c26c77e61fc31f8390c83367a8e7d2c02910b5370fdfa50d06bca349e2bc2d' 
  AND token = '1XgN9vXU3CKaIv8zmh6nf9fws2SAzMPtJBXqEX1+y7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}