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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e87ea41ab6e2d6b4066f153cc38b5319f9e26b3c8201fe78575822f5bbcd4a4' 
  AND token = 'VzsMs4maY7+lOWq4VXeUWj1n7bHadXdZjhMnrZj+rc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}