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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0045a1f65e3a74e8536b4a45719396736d82c978de37945919e2fdfb4a64239' 
  AND token = 'tcWdB/oZZaZJsMrx0edxjbXnMbUemckxP+RD0Oxy1Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}