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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38898e91a5f7f5498f9effda30aba1dc7700953d47597d19138f92a314a96bac' 
  AND token = 'RHo8q6RTx0yiY5O9DpZ7vOPvb6HVemM9T1QdinabV2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}