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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c2499254657f22904a71557285109012554e00b56ebdbab285b902c8b45290' 
  AND token = '+HQ0I5vfAPOaZ5JL0KeggA+6OS3Pw5u7xRjJwGvKAEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}