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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8ef92c2d1edc8b4be54c4a73b190f2a8e0894a4e1d2d620a2028e07c7898c0' 
  AND token = 'sLLWaisT1wDAaeCWeXFZCblWiGOowKsBsfmjQa2fqBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}