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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f82db3d6973e4d68abf91c065a57e067cefd4c40d3d9c22740624d7501b0d6' 
  AND token = 'q30W3I1k5ACoDlsbsS0tTUguahHaUXEc1c2Tn3xJaGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}