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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485f3b4af855f52ff8eb2865ca76e8dfd4f2eb611b03bb6a34f61ab867f9f64f' 
  AND token = 'Fqvj6yrV4321OLagbz5MbMuFuqTkJ8PpTGsKE1LmvRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}