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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6045a4da786a6db290a4138eb03ea22aa42ba4a7cba38c68a6e1368a634e662a' 
  AND token = 'ZG37BxZ8VMgbOCcNqC2pZIrYnbQbJ30vdn+v3S96rHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}