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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf4bff81e97ed457c7f6417fa885d18af981d23fc8010d1dca44aeb09c15585' 
  AND token = '+BN6qYfmeBg36h6ar7zPgSkBzDQA4qhj19DIYabTMlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}