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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e4487a05c7f14d849b7b6e898e1b7ec8e37f5e7f1ba9232285650861412cb7' 
  AND token = 'AF4956YhRB3zYK+wP9D/IcqNfrnkbKGVq5QM129cqSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}