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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '566daf2e9cb1dc3e5afea6b438fa6bf470fdec881aabc9fa62be6c64b7b89098' 
  AND token = 'oN7Lr86P9qyUuXJObitEkiyKsvyl8S5bHZ0djSjAYIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}