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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d0e0e4feb0929942715e58ce32476d64e74cdeec605ef71253e4034a3c0488' 
  AND token = 'Ci6YTFhmPkXqY8+B6dJ7Ul3gt5i6Gpheopq41KfhGWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}