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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ab039e10ceb571eb13fe36620d3cb23f8dd2a77713266227574d4caec7b797' 
  AND token = '5mBus0K2G94QgvFVgo9mfl9WfmOShsEW1hBYdNZxaLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}