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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca5a6c2cf86195f7b231c05dccfe0e99ea3ce5d073520dab9e89a9850bd8931' 
  AND token = 'hmTcb7fOcsyvzN9ZVirRR2MD5fJ+khSrIhmHjFbDM8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}