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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b7a5cfd021c874eeb26a58d68cabe0ff5b17d9a9a5ab3c77b58960d8709689' 
  AND token = 'V1M3rvN00PNV6T6dyIIqNqdlWp9maswJJNo5a5Cu1P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}