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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39c9b4c148bf7752ee3b40da4665f37935276ce72da6fac901a2b759275d62f' 
  AND token = '+D00B82jDnI1Z9sQ1MP+3KX4LEVMNL4XqEsvi2BXkqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}