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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f71881d361f2ab18dd0b207c7d0390ff630b5434ef6ee016d7b24d5fe15ae4' 
  AND token = 'qw2O5UOhSJxQ/z4q6WyYgaKIrhe3B9lxtJ1cv0ESpcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}