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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fd1735e62d08c2a546cdd70a359c52a94d57a440971494ca95348d6678a1f4' 
  AND token = '+e5IPMMXYjYKUo+TXMku1T7IY9ZG6YcQHPe0ZUUUeDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}