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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b332aac2dae47c8e3dc3f25338a5c1a3ad61d1973817d7d7345f10fe46ada9c' 
  AND token = '2nenr/CY2RnUsaCAB2Z0hbpEHfH3oFpoZZ2voxX7cwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}