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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d1558803705df1cf1642226cd4ece87c140612f5d29efb41e30e2631cf04e36' 
  AND token = 'zwTnKsXlNkVvptIbZSxOyFeo5uZTF05WAmR/O7dLicQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}