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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f88d469da0aa5a41fc263cff1a03d7d583a4eabc66c7fd3edffdb722d260a86' 
  AND token = 'I+kcOri6zrReJCGx2Odup8G3wiP7eJZ9UGLil/kmlgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}