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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39753d709282d412371687276a54f625284931a17cc85cf046255248bd18f596' 
  AND token = 'tucaHP/r2shIGlDRw5hJp3PyJuRG0SU6JqfbRER8lKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}