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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5497ad4bb4e390587bbb06211cb8e424bbd7e19a2734cbfb355dbe8485c308fb' 
  AND token = 'xdyu1th+KZ1z5Fh1/z8hW82HcpbuL+m0Wujhl/WJyyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}