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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0952828c14fa77d916ec2be76b3b1b25f6d2ae30175d13bc0cef1d6d478308' 
  AND token = 'Xkhxybj1z3uoo6+oTK/sM8wbBoVbLxf/M2ZK9DOxxcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}