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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2afe8813b6f63cee7f6a35f9d1aa3fb9ca9364e96339e747ca17cec7e426390' 
  AND token = 'UDcFyIY9zrRr7t+ALvuwQSs7ITAGfKmzrTSg7q0VVbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}