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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ac5741fc8caef873e29a6d05c8d4c9b6f592456d544dbb993d28906a5a7d10' 
  AND token = 'p372WXNB/M4S5Il2GyWW45lCI6Nd3suUzl3n+rrYVak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}