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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3925fc9edf84726a98d32c6f7bdaedb9cb836481c069e40acd5ea7e257d6d024' 
  AND token = 'eM9gpSsxTxtKKk9qiw6jeuwgpW7H2TTDJudQsmwoMjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}