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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d46f7eb5f6dc18e29902fd91a32cd8a75b985b5250750166a950c6089be343' 
  AND token = 'mJv3FpHran+UVqS6W+W07X35y5PqxWlC3eo8i2omwGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}