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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e11d77ce7f88d5b36803020ab9782f60461cc40cc305c427dc3f73e42a1378' 
  AND token = 'S3+ZRpZ2mPL3CfOAMq5Zu52mYc2tzCa39Vv3KEKb0bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}