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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd561b43971c404fd2dd177b13ed5460f462021b3dc4fbf4303d4441e6abd4d67' 
  AND token = 'W6xX6D+1NAkTCUBQEqpDtt204pIwzsc1x81goaiQSAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}