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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616d66a6d2122e8ad2fcae0464547c546d47c73a807b0e4b50bb7ef6bd1c171f' 
  AND token = 'rZM4+FiZfdA1P4VhGEDmRx+VX3MEFH0HGxhHYWEqnZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}