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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '310a5d863d59c4aaf858390147c508059c221fe4c881d64f28651e983b1b01a5' 
  AND token = 'tZ/9E7G+SFBDcALzoW93qWT9uXdMBCAPGaQGP2tZJvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}