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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed7a2570bcb3b47f57a6871f680a1e1ca5d0f36f92af583b89c04c6602e1bc0' 
  AND token = 'ytuIeTdI9vu3vVRlTOxgG4/XFXSMb7Q39ElbZ7qsaUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}