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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122e6ca6ec7545988e206fd5db8e3e90fd4d245ed1344fc9c0054b256740c346' 
  AND token = 'NswVp0FR2yLCd02541ehh67f1qKgNUejQjcTz0oGjt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}