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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6275ad0033a0671c00aa3e357b01274fd7c148ffcd9962e81a851b09c43fde98' 
  AND token = 'v5rbaDx7FxTNxTziztb3po2KSYLRk8Rv4I/qTkETLt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}