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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c6c4a5ee41bf2d1b663edcb7176fef76b29a0df50d7a7cca416cd4ae3ffb7d' 
  AND token = 'tMlPVZ7ZsU4gjJRjGF2OG+M7rRLAM1TubFMjcJtommE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}