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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292044cdb21c5e0c58ea564fa15367c2184bd87d3975792139347efb24aca043' 
  AND token = 'ZiOE9Nke59TEu/nCtEVaSwwoelQPPeedioV/16k06vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}