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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f1697bbacb9481bf38e904c3197048742eeb98ff1f2b9c15eb9d9ec4bae5d1' 
  AND token = '4/Ni0uESG8+dQRh4WLe7dTIVWRO7xegb9G0VtV8NUcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}