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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c500e4e45c5ff328cc12a8f9815e744b3f71b84b228ce2e5a15791b62ddd2d7a' 
  AND token = 'iPVh/dIn5uoRdhOWd2lL6gB89xKC2pk3ViL7nhv9rIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}