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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eda7cda1f1432c296b545f051240ae8a918f7b225880546844010980b59f606' 
  AND token = 'VG+UaxN+5dbbm9AlF9A14i71YdbqL92sEcIKMtnEM2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}